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MeSH and Emtree terms were systematically mapped to each PICO element

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ILC3s can be further subdivided according to their expression of natural cytotoxicity receptors (NCRs): NCR + ILC3s secrete IL-22 to maintain epithelial barrier integrity, whereas NCR ILC3s mainly produce IL-17A and IL-17F, which are known to induce pathogenic inflammation 15