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However, their income statements may not show it because the companies can raise prices to offset declines in cigarette volumes

The methodology was also criticized because a normalization to either the total number of users or the frequency of drug use was not conducted, which might have biased the result toward the harms of opiate use 14 and may have underrepresented the harms of tobacco 15

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Edward Levin and colleagues at Duke University in Durham, North Carolina, investigated whether the developmental period during which rats are first exposed to nicotine makes a difference in their subsequent drive to obtain the drug