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revealed that electronic cigarette use among young people in public schools was associated with future cigarette use during the three-wave period (2013, 2014 and 2015), whereas cigarette use was not associated with future electronic cigarette use.19 In contrast, according to large-scale surveys and cross-sectional analyses of randomised controlled trials, the majority of electronic cigarette users perceive these devices as a tool to quit regular tobacco smoking.20,21 How do Electronic Cigarettes Work

Nicotine enhances human vascular endothelial cell expression of ICAM-1 and VCAM-1 via protein kinase C, p38 mitogen-activated protein kinase, NF-kappaB, and AP-1

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The findings suggest that e-cigarette use may not be harmless for metabolic health