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Limited Long-Term Research There is still limited long-term data on the safety of AOD-9604, especially with extended use

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Their ultimate role depends on whether large outcome trials demonstrate that lowering Lp(a) reduces myocardial infarction, stroke, revascularization, cardiovascular death, or aortic valve disease progression

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Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

Notably, NNMTi did not affect food intake or cause any observed side effects
