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Manufacturers generally warn against using these drugs if a person has a personal or family history of medullary thyroid carcinoma, a type of thyroid cancer, or multiple endocrine neoplasia syndrome type 2 (MEN 2), an endocrine system condition

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Zepbound is a Food and Drug Administration (FDA)-approved medication on November 2023 for chronic weight management in adults who are obese or are overweight with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol

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Accessed March 18, 2020

Compounds like cagrilintide and amylin receptor agonists offer different mechanisms for appetite regulation that may complement the metabolic changes achieved during retatrutide treatment