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They contradicted statements made by the tobacco CEOs, for example, that nicotine was kept in tobacco simply for the flavor rather than for its addictive impact.[13] They showed evidence from their experiments that when rats were taught to press a lever to receive an injection of nicotine, they increasingly did so, demonstrating not only addictive behavior, but also how users build up nicotine tolerance over time.[14] A few days after the hearing, the subcommittee obtained documents from a public relations firm retained by the tobacco industrys trade association to combat anti-tobacco criticism and legislation

Tobacco mosaic virus, due to its stability and documented immunological activity in vertebrate systems, warrants focused experimental evaluation

This is because addiction to smoking makes it hard for smokers to live stress-free in moments of abstinence as smoking has become the sole reliever of mood swings and anxiety to them

Schedule III Drugs, chemicals, or substances that have moderate to low potential for psychological or physical dependence

Krugman et al

For other uses, it is recommended to test a small amount prior to full scale use