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In contact dermatitis and atopic dermatitis, inhibition of 15-LOX inhibits podosome formation in dendritic cells, downregulates the antigen uptake and cell migration capabilities, and contributes to the alleviation of skin inflammation (Han et al., 2017)

GSTM1 null deletion eliminates Mu-class glutathione S-transferase activity the enzyme conjugating electrophilic metabolites to GSH for excretion

Another engineered streptavidin chromatographic support (Strep-Tactin) was developed for improved binding capacity towards Strep-tag II

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Nat Rev Mol Cell Biol 2008

Wichmann HE