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In bone remodeling, IL6 drives the differentiation of osteoclasts and osteoblasts 11

For all of these three contexts, however, a specific dietary regime is mandatory: On the days of tobacco ingestion the regime is strict, and for several days to weeks after the treatment, specific foods and behaviors need to be avoided

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some missense variants, especially within the collagenous domain of the protein, and a few intragenic rearrangements including (multi) exon deletions/duplications are also described [6, 7]