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Pathophysiology 13:171181

Bader, M., Muse, W., Zander, T
The present finding that the decrease in IGF-1 levels is associated with more fatigue and less vigor is in line with these former findings

In addition to oxidative stress, excessive copper ion accumulation alters energy metabolism patterns within cardiomyocytes by inducing abnormal aggregation of thioctylated proteins and loss of iron-sulfur cluster proteins in the respiratory chain complex through direct binding to thioctylated proteins in the mitochondrial TCA cycle (76)
PETROVSKY N, BUCALA R
