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The amount of dopamine released with any given puff of a cigarette is not that great compared to other drugs, but the fact that the activity is repeated so often, and in conjunction with so many other activities, ties nicotines rewards strongly to many behaviors that we perform on a daily basis, enhancing the pleasure and the motivation that we get from them

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Having a defined quit date is also important in the context of smoking cessation medicine dosing (see: A focus on pharmacological support)

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