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Over time, daily use can dull emotional responsiveness and hinder the development of healthy coping skills for stress, trauma, or emotional pain

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Nicotine is an addictive chemical that may increase heart rate and blood pressure and pose risks for individuals with certain medical conditions, particularly cardiovascular disease

Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, et al

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} : CS1 maint: DOI inactive as of July 2025 (link) "Arsenic Exposure Induces the Warburg Effect In Cultured Human Cells"