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There are several tests used to diagnose COPD, including pulmonary function tests like spirometry, imaging such as chest x-rays or CT scans, arterial blood gas tests, ECG, and even genetic testing

This persistent inflammation can lead to accelerated bone resorption and tissue degradation key features of periodontal disease

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This paradigm shifted with the advent of high-throughput sequencing technologies, particularly 16S rRNA gene profiling and shotgun metagenomics, which unveiled a complex ecosystem harboring several hundred to over a thousand microbial species across the nasopharynx to alveoli [89]

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