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MS/MS was performed using an AB Sciex Triple Quad 4,500 system (Applied Biosystems, Foster City, CA, USA)

We utilized the solvent extraction method (using isopropanol) and instrumental analysis methods (using gas chromatography/mass spectrometry (GC/MS)a method to identify different substances within a test sample) as described in prior studies of cigarettes purchased in Mexico, 16 and kreteks (clove + tobacco cigarettes) and cigarettes purchased in Indonesia