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In astrocytes, APOE4 increased de novo cholesterol synthesis despite intracellular cholesterol accumulation caused by lysosomal sequestration

monocytogenes , but not in the glyoxalase mutants (Fig 5C)

Next, 30 L of the worm solution was retrieved and placed on slides, covered by coverslips, and observed under the orthogonal fluorescence microscope (Axio Scope.A1, Carl Zeiss, Inc., United States)

97 The ultra-sensitive quantitative HBsAg assay has an LLOD of 0.0005 IU/mL which is 100-fold lower than those of conventional HBsAg assays