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The most widespread of these is a mutational signature already found in all cancers

doi: 10.1016/j.jacc.2015.07.037

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[DOI] [PubMed] [Google Scholar] Cong X.X., Gao X.K., Rao X.S., Wen J., Liu X.C., Shi Y.P., He M.Y., Shen W.L., Shen Y., Ouyang H., Hu P., Low B.C., Meng Z.X., Ke Y.H., Zheng M.Z., Lu L.R., Liang Y.H., Zheng L.L., Zhou Y.T

However, the report finds that most states continue to fall short in funding these lifesaving programs: This year (fiscal year 2026), the states will spend $728.6 million on tobacco prevention and cessation programs, which is less than a quarter (22%) of the $3.3 billion recommended by the CDC for all states combined