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77 In 2021, the WHO, AHA, ACC, and ESC issued a joint tobacco endgame statement, calling for accelerated global action to eliminate tobacco use as a driver of CVD and premature mortality 25 In their recent 2025 report, the European Environment Agency (EEA) firmly rejects the tobacco industrys harm reduction narrative

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A majority of the genes the team identified have unknown functions, so the researchers will try to understand their functions and how changes in those genes, their function and interaction with the environment affect the risk for addictive behaviors