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Nicotine enters your bloodstream within seconds, reaches the brain, and releases dopamine

Pathogenesis Imbalance between mucosal defensive factors and aggressive factors Defensive Factors Prevent the stomach and duodenum from being harmed (self-digestion)

Smoking rates have been dropping for years, but the habit remains the leading cause of preventable death and disability in the United States, responsible when combined with secondhand smoke for about 1 in 5 deaths, according to the Centers for Disease Control and Prevention

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