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Overall, the researchers found no association between donor smoking, pack-years of smoking or substance use and primary graft dysfunction at any time point

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"Early exposure to tobacco during pregnancy apparently affects the individuals response to cigarettes in later adolescence and adulthood." The researchers statistical analyses indicated that the associations between maternal smoking during pregnancy and offsprings future smoking were independent of socioeconomic status, maternal age at pregnancy, offspring sex, and offspring age at the time of the interview