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However, excessive iron leads to the accumulation of reactive oxygen species within cells, disrupting intracellular redox balance, inducing mitophagy, membrane rupture, and lipid peroxidation, which can damage tissues and cells, ultimately resulting in ferroptosis

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Meldonium enhanced the morphology, antioxidant capacity, and ATP production of mitochondria and inhibited the opening of the mitochondrial permeability transition pore in the cerebral cortex and hippocampus during cerebral ischemiareperfusion injury (CIRI) in rats

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