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Studies that included pregnant women and those that focused on smoking harm reduction or relapse prevention were excluded

Federal Not applicable under Federal law State Retailers are required to conspicuously post at the point of sale and maintain the following three (3) signs with lettering at least 1/2 inch in height which states: THE SALE OF TOBACCO OR ELECTRONIC CIGARETTES TO PERSONS UNDER 21 YEARS OF AGE IS FORBIDDEN BY INDIANA LAW

In the United Kingdom smoking prevalence has decreased from 46% during the 1970s to about 15% in recent years (West and Brown, 2019)

In its annual reports, Philip Morris International boasts a high rate of conversion to IQOS, estimating that about 70 percent of its users have switched completely (defined internally as using heated tobacco for at least 95 percent of their consumption)

One of these restrictions was raising the minimum age to purchase tobacco products from 18 to 21

doi:10.1097/YCO.0b013e3283459242