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All subjects (non-smokers, asymptomatic cigarette smokers, and smokers with oesophagitis) were studied postprandially with a lower oesophageal sphincter sleeve assembly, distal oesophageal pH electrode, and submental electromyographic electrodes

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Notably, gastrointestinal toxicity was more pronounced in animals administered EGCG via gavage or when fasted, whereas administration via diet, water, or capsule resulted in milder effects (234, 243)

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