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Venous blood samples for plasma nicotine analyses were drawn starting 5 min prior to use of the study product (baseline) and subsequently at 1, 3, 4, 5, 6, 7, 9, 11, 15, 30, 45, 90, 180, and 240 min following start of product use (Supplementary Table S1)

First of all, WHY DOES SMOKING BECOME ADDICTIVE

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The second-hand aerosol is not harmless water vapor. It places others at risk of exposure to nicotine and other chemicals that can be harmful to their health

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Increasing awareness of the links between smoking and RA, including passive smoking (especially in childhood), is a first step that could reduce smoking among people at risk of RA