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Bioinformatic methods also showed applications in investigating the impact of tobacco smoke on regulatory factors associated with gene expression in various ways, for example, an aberration in DNA methylation (71, 72), transcriptional binding sites (73), and noncoding RNA (70, 74, 75)

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The conscription process involves a lottery system at the district level for men aged 21 and older, as well as voluntary selection for those aged 1820 [19, 21]