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Abbreviations: APESCGIT adverse physiological effects of smoking cessation on the gastrointestinal tract GIT gastrointestinal tract nAChRs nicotinic acetylcholine receptors Data sharing not applicable to this article as no datasets were generated or analyzed during the current study

Between 2005 and 2030, 135.1 million people will have died worldwide in developing nations because of smoking-related illness, according to the World Lung Foundation

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Require designs that facilitate social interaction and build social connection consistent with best practices from organizations such as Happy Cities or Reimagining the Civic Commons

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