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To evaluate the cardiovascular outcomes of glucagonlike peptide1 receptor agonists (GLP1RA) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD)

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Pre-treatment with a GLP1 receptor-blocking antibody neutralised the CNO-dependent improvement in glucose tolerance but did not affect the reduction in food intake, and an independent group of animals pair-fed to the CNO-treatment group demonstrated attenuated weight loss

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