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During a calorie deficit, depleted glycogen stores prompt the liver to produce ketone bodies, including acetone, which is exhaled through the lungs and causes a fruity or nail-varnish-like breath odour known as 'keto breath'

On the 0.25 mg starter dose a 10 mg vial technically contains 40 doses, but punctured vials generally must be discarded after 28 days to prevent bacterial contamination, so a large vial used for a starter dose often means wasted medication

Haugen, B, Pacini, F, Reiners, C, et al

Tirzepatide Products (Mounjaro, Zepbound) Tirzepatide functions through dual GLP-1 and GIP receptor activation with a half-life around five days