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Hemphill said in the statement

Smoking may also increase the frequency and severity of GERD symptoms

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A population-based case-control study of marijuana use and head and neck squamous cell carcinoma

And one oft-circulated behind-the-scenes anecdote captures that confidence: Pitt reportedly turned to Edward Norton at the Venice premiere and said it was the best movie Im ever going to be in, a line thats become part of the films mythos as much as any twist ending