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In adults, doses of 3 mg daily appeared to be more effective than 2 mg doses, and a treatment duration of 3 months was more likely to be related to a beneficial outcome

Also, the plasma levels of alarmins were lower in ALA-treated patients

Philadelphia, Elsevier Saunders 2012;571-592

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes

7: 369386 [DOI] [PMC free article] [PubMed] [Google Scholar] 124.Matejkova O., Mustard K
