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You've likely heard the buzz about GLP-1s

All you want is to feel better, but you feel frustrated and unheard because what you have been doing isnt working

GLP-1 enhances insulin secretion, suppresses glucagon release, and promotes satiety, resulting in reduced food consumption and subsequent weight ...

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Moreover, it remains to be shown that GIPR agonism can improve insulin secretion in type 2 diabetic patients who have been noted in previous studies to be unresponsive to GIP

The authors found that the number of GLP-1 expressing cells is consistently reduced at the site of active disease in both mouse models of intestinal inflammation and in CD patients, as confirmed by the single-cell RNA sequencing data