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The disease has classically been characterised by serum increases in the pro-inflammatory cytokines tumour necrosis factor (TNF), interferon-gamma (IFN), IL-17 and IL-23

2017 doi: 10.1016/j.drugalcdep.2017.07.009

"But this also represents good news for smokers, because it means that much of their increased risk for cardiovascular disease goes away quickly, too, once they stop smoking," he explains

Finish with a nightly fluoride rinse to help protect enamel and rinse with water immediately after each cigarette to reduce fresh tar residue and potentially lessen staining