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It is not necessary to inhale the produced vapor into the lungs to create the effect

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Delayed healing of the wound: Vascular constriction, brought on by smoking, reduces blood flow and slows healing

Elevated plus maze (EPM)- The Elevated Plus Maze (EPM) test is used to assess anxiety-related behavior in rodent models of CNS disorders

Summary Keywords adolescents, e-cigarettes, nicotine addiction, prevention strategies, public health, vaping Citation Fainardi V, Barbetta E, Petz M, Rizzo L, Ruberti F and Esposito S (2026) The new nicotine epidemic: understanding the systemic harms of e-cigarettes in the adolescent population