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Wang, Fibroblasts and myofibroblasts in wound healing: force generation and measurement
The primary endpoint was the change in endothelial function, as assessed by brachial FMD
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68,69 This overactivation of NAD+-consuming pathways with age and disease can severely compromise NAD+ availability in cells, subsequently limiting utilization of NAD+ by other critical NAD+-dependent enzymes that promote good health, such as the SIRTs
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