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Chapter 5 summarizes the health benefits of smoking cessation for all-cause mortality in the general population

With a 2% (20mg) nicotine strength, it provides a balanced throat hit that feels smooth yet satisfying

The quitters showed greater GM volume than the relapsers in the right postcentral gyrus, right putamen\caudate nucleus and left orbitofrontal cortex (OFC)

On day 7, OM was observed in 80% of ears in the CS + OM group and 30% in the OM group

Because of this difference, patients and physicians have high expectations with little tolerance for complications

Advanced models like the CFAX12 integrated with a lung-on-chip technology are crucial for bridging this gap, providing a more physiologically relevant platform to study CS-induced lung damage
