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Smoking can elevate the LDL, or bad, cholesterol in your blood and decrease HDL, or healthy, cholesterol

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Additionally, individuals with ADHD who smoke may experience an increased risk of nicotine withdrawal symptoms when ceasing nicotine use

There is some evidence from a theoretical mechanistic study to suggest that nicotine degradation may be more rapidly initiated as temperature is reduced which was proposed by the authors to suggest that heated tobacco products may be more likely to experience nicotine degradation than conventional cigarettes (Chavarrio Caas et al., 2021)
