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(2021) G6PD deficiency, redox homeostasis, and viral infections: implications for SARS-CoV-2 (COVID-19)

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It also inhibited cell proliferation

The recent discovery of the small molecule N6F11, which binds the tripartite region of Trim25 and promotes proteasome-degradation of GPX4 in pancreatic cancer cells, while sparing immune cells and the anti-tumoral response of the microenvironment, could represent a major clinical breakthrough for the use of GPX4 inhibitor/degrader [61]