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Furthermore, metabolites including flavonoids, organic acids, alkaloids and amino acids play a vital role in determining the quality of cigar ( The advancement of microbial sequencing technologies ( This study utilized continuous flow analysis technology, metagenomic sequencing, and widely targeted metabolomics to comprehensively analyze the dynamic changes in relevant chemical substances, microbial communities, and metabolic products during the fermentation process of CTLs

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However, the study design may have limited the findings of this study