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In Science Translational Medicine on November 2, 2011, the scientists reported that mice given nicotine in their drinking water for 7 days showed increased activity in response to cocaine

for its cigarette tax of $1.20 per pack (enacted July 2016), compared to the national average of $1.82

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Cannabis potency has been increasing worldwide, and several studies found some evidence of links between dose-related use of cannabis and an increased risk of developing a psychotic illness

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