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While a decrease in e-cigarette use was observed among high school students, among middle school students there was an increase in current overall tobacco product use from 4.5% to 6.6%

Unlike e-cigarettes, which heat a nicotine-containing liquid, HNB products heat tobacco itself

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Smoking Cigarette Smoking and Cancer National Cancer Institute Smoking & Tobacco Use Centers for Disease Control Smoking Our World in Data Treating Tobacco Use and Dependence U.S

Allelochemicals block the series of enzymatic intermediates (-amylase, phosphorylase, etc.) necessary for seed germination 73