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Cigarette use has decreased, but use of electronic cigarettes has increased substantially in the United States, from 0.6% of middle school students in 2011 to 10.5% in 2019, and from 1.5% of high school students in 2011 to 27.5% in 2019

Archived from the original on 17 October 2002

Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO

This level of usage increases the risk of addiction and potential adverse health effects

The IARC monographs also referenced studies involving rabbits and dogs that were much less conclusive

We found that, even after factoring in the heterogeneity between studies and other sources of uncertainty, smoking has a strong-to-very-strong association with a range of health outcomes and confirmed that smoking is irrefutably highly harmful to human health