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It also contains climate-warming carbon dioxide, methane and nitrous oxides

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Ferdinand RF, Blm M, Verhulst FC

An umbrella review of global evidence also concluded that throat irritation is one of the most consistently reported short-term side effects of e-cigarette use, while evidence linking vaping directly to throat infections remains limited

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Juul has previously stated it believes it submitted enough information to "address all issues raised by the agency." Its unclear if Juul will be able -- or be required -- to submit any further data while the FDA conducts the additional review