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In mid-2021, the State Health Plan had just 2,795 users of a GLP-1 medication for weight loss

One of three receptors activated by Retatrutide

Placebo arms in these trials lost much less weight

Keywords: Heart failure with reduced ejection fraction (HFrEF), GLP-1 receptor agonists (GLP-1 RAs), Type 2 diabetes mellitus (T2DM), Cardiovascular outcomes, Dipeptidyl peptidase-4 inhibitors (DPP4i) 1

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GI symptoms include stomach upset, nausea, vomiting, diarrhea, and constipation