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We propose that a c-Glue strategy could be used to target related E3 ligase families with positively charged pockets that accommodate endogenous phosphodegrons (for example, F-box and SOCS-box proteins) 24,25 or protein C-terminal acids (that is, C-degron pathway E3 ligases) 26,27,28

Mouse Anti--Tubulin antibody was used as a loading control (1:5000, ab6046, Abcam)

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Monomict : A combination of two Greek word elements, miktos meaning mixed or mingled, and monos meaning one or single

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[PMC free article: PMC9362726] [PubMed: 35514292] [CrossRef] 467