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Description
Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF-1 under normoxia

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Similar results were also observed in a group of current consumers of combustible tobacco products who exhibited a decrease in oxidative stress four months after switching to ENDS use, even when nicotine was still present [132]

The ordinance aims to reduce tobacco product waste, which is a significant contributor to plastic pollution and environmental harm
The health implications include a greater risk for cancer of the esophagus, throat, voice box, lips, and tongue
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