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The updated model estimates suggest that between 1989 and 2019, the CTCP has prevented a total of 9.5 million person-years of smoking and 15.7 billion packs of cigarette consumption (worth $51.4 billion in pre-tax sales to the tobacco companies), and saved between $544 billion (NIPA) and $816 billion (CMS) in healthcare expenditure

A novel mutation in GJA3 (connexin46) for autosomal dominant congenital nuclear pulverulent cataract

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Corey CG, Ambrose BK, Apelberg BJ, King BA

Also, these studies typically dont evaluate the cognitive deficits that happen with nicotine withdrawal between doses or during longer-duration efforts to quit nicotine