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The main substance that brings about this form of addiction is nicotine, a stimulant naturally found in the leaves of the tobacco plant
Morphological studies of bronchial mucosal biopsies from asthmatics before and after ten years of treatment with inhaled steroids

doi: 10.1007/s11356-023-30542-4, PMID: [DOI] [PubMed] [Google Scholar] 8.Lee SH, Yun Y, Kim SJ, Lee EJ, Chang Y, Ryu S, et al

People with existing mental health issues may experience adverse effects when using cannabis

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It was also required because residual life expectancy had rapidly increased in England between 1966 and 2007 [24]