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Exposure to air causes the tobacco to dry out and lose flavour , making for an unpleasant smoking experience

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Furthermore, other cytokines, such as CXCL5/10/16, MMPs, Osteopontin, Proliferin, VEGF, and TNF are secreted from BC cells after E-cig treatment, which prompts tumor progression and metastasis

They are also more likely to have complications, including blood clots, irregular heartbeat, and kidney failure