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Benowitz NL, Porchet H, Sheiner L, & Jacob P (1988) Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum

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Interestingly, the effect of smoking on CKD progression varied depending on CKD stage (Figure 1)

The FDA can withdraw marketing orders if the agency determines, among other things, the benefits no longer outweigh the risks, like a notable increase in use of the products among youth or former smokers, the agency said

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doi:10.1016/j.jaci.2009.10.052