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They required the following inclusion criteria: Focus on healthy people Data on the prevalence of xerostomia in e-cigarette and/or combustible tobacco users Observational studies Out of 1,074 published articles, three were selected for review by two independent researchers, and any disagreements between the two were resolved by a third researcher

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Cross-Sectional (2021, Age 2040): Smokers had lower TT, higher estradiol, and lower T:E2 than non-smokers

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