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Results from these studies strongly suggest that, in healthy populations, existing generic measures are not sensitive enough to detect change over time when stopping or switching from cigarettes to other TNPs, owing to high ceiling effects [20]

Vapings potential for harm reduction may be greatest among vulnerable populations of smokers, such as individuals living with mental health challenges or regular non-nicotine substance use that have been resistant to existing smoking cessation efforts

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Unfortunately, by then they are addicted to the nicotine and have a hard time quitting, so it becomes a vicious cycle," the American Lung Association's Chief Medical Officer Dr