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On the other hand, most human medullary thyroid carcinomas and hyperplastic C cells express GLP-1R (75, 77) (Figure 2)

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Advances in drug development have led to dual agonists such as tirzepatide, which target both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors and produce greater weight loss than single-receptor agonists

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